Vorobiova Viktoriia, I. Sikorsky National Technical University of Ukraine «Kyiv Polytechnic Institute» (37 Pobeda Av., 03056 Kyiv, Ukraine)

Chyhyrynets Olena, I. Sikorsky National Technical University of Ukraine «Kyiv Polytechnic Institute» (37 Pobeda Av., 03056 Kyiv, Ukraine)

Shakyn Anastasia, I. Sikorsky National Technical University of Ukraine «Kyiv Polytechnic Institute» (37 Pobeda Av., 03056 Kyiv, Ukraine)

Language: ukrainian


Urgency of the research. Environmental sustainability concerns and the elevated costs of developing synthetic products created the trend in the manufacture of cosmetic products aimed primarily at creating new recipes using complex biologically active substances (BAS) from natural products.

Target settingю. Therefore, the actual problem is finding promising types of plant material for obtain practically important compounds.

Actual scientific researches and issues analysisIn earlier works by authors can also find information about possible applications of the crests of grapes and its 2-propanol extracted compounds for the development of products with a biological value. However, the extract contains a small amount of water-soluble antioxidants, which is due the type of extractant.

Uninvestigated parts of general matters defining. At the same time still not clarified the Possibility Use of other waste industry grape such as grapes of pomace for obtaining compounds of natural origin.

The research objective. In this sense It is necessary a comparative study of the quality of the different grape pomace extracts when used for extraction 2-propanol and aqueous 2-propanol solution.

The statement of basic materials. By gas chromatography-mass spectrometry (GC-MS) studied component composition of the isopropanol extract of grape pomace (family Vítis varieties Vitislabrusca × Vitisvinifera.). As part of the isopropanol extract of grape pomace contains 22 individual component present in an amount greater than 0.1%. Analysis of the composition indicated that the main components are the aldehydes (caproic, enanthic, phenylacetaldehyde, butanal, nonanal, citral), fatty acids (hexadecanoic, linoleic and (9Z)-Oktadetsenovaya acid), as well as terpene compound. As part of the water-isopropanol extract further identified phenolic compounds.. Infrared spectral analysis confirmed the presence of functional groups which are established by connections.

Conclusions A significant portion of biologically active substances comprise aldehydes and fatty acids. Confirmed ability to use 2-propanol and aqueous 2-propanol extracts pomace grape to create cosmetics and products with high biological value.

Key words:

Grapes V. Labrusca, 2-propanol, water 2-propanol, extract, gas chromatography-mass spectrometry, alcohols, aldehydes, terpene compounds


  1. Laura Rubióa, Maria-José Motilvaa, Maria-Paz Romeroa (2013). Recent Advances in Biologically Active Compounds in Herbs and Spices: A Review of the Most Effective Antioxidant and Anti-Inflammatory Active Principles. Critical Reviews in Food Science and Nutrition, vol. 53, issue 9, рp. 943–953.

  2. Elena M. Balboaa, Daniele R. Nogueirac, Noelia González-López (2014). Potential of antioxidant extracts produced by aqueous processing of renewable resources for the formulation of cosmetics. Industrial Crops and Products, vol. 58, рр 104–110.

  3. Hegde, Sachet. A. (2016). Review of the Medicinal Properties, Phytochemical and Biological Active Compounds of Tinospora sinensis (Lour.) Merr. Journal of Biologically Active Products from Nature, vol. l. 6, issue 9, рp. 84–94.

  4. Vorobyova, V.I., Chygyrynets, E.E., Efimova, V.G., Pilipenko, T.N., Pichakhchi, V.A. (2016). Izuchenie komponentnogo sostava biologicheski aktivnyih soedineniy spirtovogo ekstrakta grebney vinograda [The research component composition of biologically active compounds alcoholic extract crest grapes]. Tekhnichni nauky ta tekhnolohiyi – Technical Sciences and Technologies, no. 2 (4), pp. 189–195 (in Ukrainian).

  5. Sydorov, Yu.I., Hubytska, I.I., Konechna, R.T., Novikov V.P. (2008). Ekstraktsiia roslynnoi syrovyny [Extraction plant material]. Lviv: Vydavnytstvo Natsionalnoho universytetu «Lvivska politekhnika» (in Ukrainian).

  6. Eremina, A.V., Popkov, V.A., Degtiareva, E.A.,. Reshetniak, V.Iu. (2003). Biologicheski aktivnye veshchestva vinograda: klassifikatsiia, farmakologicheskie effekty, lekarstvennye preparaty i BAD na ikh osnove [Biologically active substances of grapes: classification, pharmacological effects, medications and dietary supplements based on them]. Naturoterapiia i gomeopatiia – Naturoterapy and Homeopathy, no. 4. рр. 27–30 (in Russian)

  7. Francisco J. Pérez, Camilo Viani and Julio Retamales (2000). Bioactive Gibberellins in seeded and seedless grapes: Identification and changes in content during berry development. American journal of enology and viticulture, vol. 51, рp. 315–318.

  8. Dorman H.J.D., Deans, S.G. (2000). Antimicrobial agents from plants: antibacterial activity of plant volatile oils. Journal of Applied Microbiology, vol. 88, рр. 308–316.

  9. Ben Arfa A., Combes S., Preziosi-Belloy L, Gontard N., Chalier P. (2006). Antimicrobial activity of carvacrol related to its chemical structure, Lett. Appl. Microbiol., vol. 43, issue 2, рр. 119–236.

  10. Boukhebti H., NadjibChaker A., Belhadj H., Sahli F., Ramdhani M., Laouer H., Harzallah D. (2011). Chemical composition and antibacterial activity of Menthapulegium L. and Menthaspicata L. essential oils. Der Pharm. Lett, vol. 3, no. 4. рp. 267–275.

  11. Anna Maria Papini (2010). Cosmetics toward peptide-based cosmeceutics. Chimica Oggi-Chemistry Today, vol. 8 (6), рp. 3–5.

  12. Suresh C. Rastogi, Jeanne D. Johansen, Torkil (1996). Menne Natural ingredients based cosmetics. Contact Dermatitis, vol. 34, рр. 423–426.